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Voltaren

Generic Voltaren is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Generic Voltaren is used to treat pain or inflammation caused by arthritis or ankylosing spondylitis. Generic Voltaren works by reducing hormones that cause inflammation and pain in the body.

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Also known as:  Diclofenac.

Description

Generic Voltaren is used to treat pain or inflammation caused by arthritis or ankylosing spondylitis.

Generic Voltaren is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Generic Voltaren works by reducing hormones that cause inflammation and pain in the body.

Voltaren is also known as Diclofenac, Voveran, Voltarol, Voltarol SR, Voltarol Retard, Voltarol Rapid, Diclomax SR, Diclomax Retard, Motifene, Defenac, Diclofex, Diclozip, Dyloject, Fenactol, Flamrase, Flamatak, Econac, Rhumalgan SR, Rhumalgan XL, Volsaid SR.

Generic name of Generic Voltaren is Diclofenac.

Brand names of Generic Voltaren are Cataflam, Voltaren, Voltaren-XR.

Dosage

Take Generic Voltaren orally.

Do not crush or chew the pill. Swallow it whole.

Take Generic Voltaren with great amount of water.

Take Generic Voltaren with or without food.

If you want to achieve most effective results do not stop taking Generic Voltaren suddenly.

Overdose

If you overdose Generic Voltaren and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Voltaren overdosage: nausea, vomiting, stomach pain, black or bloody stool, shallow breathing, fainting, coma.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Voltaren are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Voltaren if you are allergic to Generic Voltaren components or to aspirin or other NSAIDs.

Do not take Generic Voltaren if you are pregnant, planning to become pregnant. Do not breast-feed while taking Generic Voltaren.

Do not take Generic Voltaren if you just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

Be careful with Generic Voltaren if you use any other over-the-counter cold, allergy, or pain medicataion.

Be careful with Generic Voltaren if you had a history of heart attack, stroke or blood clot, heart disease, congestive heart failure, high blood pressure, liver or kidney diseases, asthma, polyps in the nose.

Be careful with Generic Voltaren if you smoke.

Be careful with Generic Voltaren if you take antidepressants, blood thinner (Coumadin); cyclosporine, lithium, methotrexate, you take diuretics, you take steroids.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds).

Avoid alcohol.

It can be dangerous to stop Generic Voltaren taking suddenly.

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Discharge time, necessity of diclofenac and postoperative VAS values at 0-1 hours were statistically lower in Group 1 patients than the Group 2 patients (p<0.05). Difficulties, like straining, cough, laryngo-bronchospasm, vomiting and nausea during extubation, were 5% and 25% in Group 1 and Group 2, respectively, but these differences were not statistically significant (p=0.077).

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There was no significant difference between the two groups with regard to age, gender, VAS, FEV(1), PEFR, serum cortisol and glucose levels, necessity for additional analgesia and hospital staying days. In contrast, adverse effects and duration of catheterisation were statistically significantly lower in group PVB (p=0.001 and p<0.001, respectively).

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Polacrilin potassium is an ion exchange resin used in oral pharmaceutical formulations as a tablet disintegrant. It is a weakly acidic cation exchange resin. Chemically, it is a partial potassium salt of a copolymer of methacrylic acid with divinyl benzene. It ionizes to an anionic polymer chain and potassium cations. It was hypothesized that polacrilin potassium may be able to improve the permeability of anionic drugs according to the Donnan membrane phenomenon. The effect of polacrilin potassium on the permeability of diclofenac potassium, used as a model anionic drug, was tested in vitro using diffusion cells and in vivo by monitoring serum levels in rats. The amount of drug permeated across a dialysis membrane in vitro was significantly more in the presence of polacrilin potassium. Significant improvement was found in the extent of drug absorption in vivo. It could be concluded that polacrilin potassium may be used as a high-functionality excipient for improving the bioavailability of anionic drugs having poor gastrointestinal permeability.

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Dexamethasone and diclofenac were equally effective in reducing postoperative inflammation after phacoemulsification and IOL implantation in eyes with no other disease than cataract. Both substances were more effective than placebo.

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Two manganese(III) porphyrins: manganese(III) tetraphenylporphyrin chloride and manganese(III)-tetrakis(3-hydroxyphenyl)porphyrin chloride were tested as ionophores for the construction of new diclofenac-selective electrodes. The electroactive material was incorporated either in PVC or a sol-gel matrix. The effect of different plasticizers and additives (anionic and cationic) on the potentiometric response was studied. The best results were obtained for the PVC membrane plasticized with dioctylphtalate and having sodium tetraphenylborate as a lipophilic anionic additive incorporated. The sensor response was linear in the concentration range 3 × 10(-6) - 1 × 10(-2) M with a slope of -59.7 mV/dec diclofenac, a detection limit of 1.5 × 10(-6) M and very good selectivity coefficients. It was used for the determination of diclofenac in pharmaceutical preparations, by direct potentiometry. The results were compared with those obtained by the HPLC reference method and a good agreement was found between the two methods.

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Forty female SD rats were randomly and averagely divided into four groups: the normal, model, acupuncture and control group. The method of heel tendon resection for unilateral hind limb was used to establish OA animal models-that was to cut off the rat's heel tendon of left hind limb. The acupuncture group and control group were respectively treated by electro-acupuncture and Diclofenac on right hind limb of each animal for 2 weeks. Immunohistochemical staining was used to observe the expression characteristic of IL-1beta and TNF-alpha in cartilage of each group,and the differences were compared among the groups.

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Pain is a common symptom after surgery in children, and the need for effective pain management is obvious. For example, after myringotomy, despite the brief nature of the procedure, at least one-half of children have significant pain. After more extended surgery, such as tonsillectomy, almost all children have considerable pain longer than 7 days. Nonsteroidal anti-inflammatory drugs (NSAIDs) are useful for postoperative pain management because surgery causes both pain and inflammation. Several pediatric studies indicate NSAIDs are effective analgesics in the management of mild and moderate pain. In the treatment of severe pain, NSAIDs should be given with acetaminophen (paracetamol) or opioids, and the use of an appropriate regional analgesic technique should be considered. NSAIDs are more effective in preventing pain than in the relief of established pain. Pain following surgery is best managed by providing medication on a regular basis, preventing the pain from recurring. This proactive approach should be implemented for any procedure where postoperative pain is the likely outcome. In children, the choice of formulation can be more important than the choice of drug. Intravenous administration is preferred for children with an intravenous line in place; thereafter mixtures and small tablets are feasible options. Children dislike suppositories, and intramuscular administration should not be used in nonsedated children. Ibuprofen, diclofenac, ketoprofen and ketorolac are the most extensively evaluated NSAIDs in children. Only a few trials have compared different NSAIDs, but no major differences in the analgesic action are expected when appropriate doses of each drug are used. Whether NSAIDs differ in the incidence and severity of adverse effects is open to discussion. Because NSAIDs prevent platelet aggregation they may increase bleeding. A few studies indicate that ketorolac may increase bleeding more so than other NSAIDs, but the evidence is conflicting. Severe adverse effects of NSAIDs in children are very rare, but it is important to know about adverse effects in order to recognize and treat them when they do occur. NSAIDs are contraindicated in patients in whom sensitivity reactions are precipitated by aspirin (acetylsalicylic acid) or other NSAIDs. They should be used with caution in children with liver dysfunction, impaired renal function, hypovolemia or hypotension, coagulation disorders, thrombocytopenia, or active bleeding from any cause. In contrast, it seems that most children with mild asthma may use NSAIDs.

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To compare the efficacy and safety of two different doses of celecoxib and diclofenac in the treatment of Norwegian patients with ankylosing spondylitis.

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voltaren gel costochondritis 2016-06-13

Compared with saline, betamethasone and diclofenac significantly decreased early-phase conjunctival inflammation. Betamethasone significantly inhibited corneal haze formation compared with saline at 3 to 5 and 8 to 12 weeks. Diclofenac did not inhibit corneal haze formation significantly. Although betamethasone tended to Buy Generic Viagra be more effective in inhibiting corneal haze formation and deposition of type IV collagen than diclofenac, there was no statistical difference between the 2 anti-inflammatory agents.

voltaren gel otc 2016-09-22

Systemic enzyme therapy with bromelain resembles a sensible alternative to nonsteroidal antiinflammatory drugs for the treatment of sports injuries, with particular consideration of therapeutic benefits and possible risks. Beyond aftertreatment of sports injuries, bromelain is used postoperatively as well. Besides the desired effects remission of oedema and pain relief, however, the postoperative use of bromelain raises uncertainty in some patients and physicians since an enhanced bleeding tendency in case of concomitant therapy with anticoagulants was described as a possible interaction. Therefore, the goal of this Lanoxin Tablets study was to investigate the clinical relevance of this interaction.

voltaren 100 mg 2017-01-12

In this randomized, open-label, crossover, comparative bioavailability study, 42 healthy subjects (mean age 23.2 years) were given a single dose of diclofenac-K Paracetamol 500mg Dose 25 mg liquid capsule or 2 × 12.5 mg tablets over 1-day treatment periods, separated by a washout period of 14 days.

voltaren topical dosage 2016-11-29

This pilot study showed that topical treatment with S. ebulus gel can be recommended for alleviating symptoms of patients with knee OA. However, longer trials involving larger samples size, are needed for Casodex High Dose achieving a comprehensive understanding about the efficacy and safety of S. ebulus in knee OA.

voltaren 25mg capsules 2015-09-07

The Ch-based matrix was a reliable colonic controlled-release system for 5-ASA (t(50) =1.97 h) or DS (t(50) =3.58 h). For in vivo application, a number of matrices adequate to make up the therapeutic drug dose should be Voltaren Mg introduced into enteric-coated size 00 capsules.

voltaren cream medicine 2015-03-30

Dyspepsia and related gastrointestinal (GI) symptoms are commonly reported by patients taking nonspecific nonsteroidal anti-inflammatory drugs (NSAIDs) and significantly impact treatment effectiveness, cost, and quality of life. This Aciphex Dosage Instructions study sought to evaluate dyspepsia-related health in osteoarthritis (OA) and rheumatoid arthritis (RA) patients taking valdecoxib compared with patients taking nonspecific NSAIDs.

voltaren pill high 2016-03-28

This paper reports the synthesis of magnetic and pH-sensitive beads derived from κ-carrageenan and carboxymethyl chitosan for drug delivery. The magnetic Fe3O4 nanoparticles were synthesized inside a mixture of biopolymers by in situ method. The structural properties of hydrogel beads were characterized by TEM, SEM, XRD, and VSM techniques. The swelling ratio of beads indicated pH-dependent properties with maximum water absorbing at pH 7.4. Introducing magnetic nanoparticles caused a decrease in swelling capacity from 16.4 to 10 g/g. Drug loading and release efficiency were investigated using diclofenac sodium as a model system. The in vitro drug release studies exhibited significant behaviors on the subject of physiological simulated pHs and external alternative magnetic fields. The maximum cumulative release was around 82% at pH 7.4. The presence of magnetite nanoparticles certainly influenced the drug release patterns. The response of beads Zyrtec Generic Target to external stimulus makes them as good candidates for novel drug delivery systems.

voltaren dosage 50mg 2015-05-02

The pharmacokinetics of diclofenac after a single oral dose (50 mg) were studied in 10 healthy adults on two occasions separated by 2 weeks, once in the morning (dose administered at 07.00 h) and once in the evening (dose at 19.00 h). Peak serum drug concentrations as well as the area under the drug concentration-time curve were significantly less during the night compared with the day (Cmax: 1886 +/- s.d 901 vs 2791 +/- 1565 ng ml-1 and AUC: 2807 +/- 1376 vs 3681 +/- 1986 ng ml-1 h). Hyzaar 125 Mg However, the time to reach peak concentration (tmax) and the half-life of diclofenac (t1/2) were not significantly different on the two occasions. We suggest that the extent of diclofenac absorption is slightly lower following administration in the evening compared with administration in the morning.

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The ketamine group showed significantly lower pain scores both at rest and on swallowing, with less total paracetamol consumption (P < 0.05) during the 24 h after surgery. Significantly more patients required postoperative morphine titration in the control group (P < 0.05). The time to the first oral intake, and duration of i.v. hydration, were significantly shorter and Amoxil Y Alcohol the quality of oral intake was significantly better in the ketamine group (P < 0.05). There were no differences in the incidence of vomiting or dreaming between the groups.

voltaren dose range 2016-12-01

The therapeutic effectiveness and tolerability of the topical administration of a gel elaborated with a standardized Sphaeralcea angustifolia extract applied to patients with Nexium Medicine Dosage Hand osteoarthritis (HOA) was evaluated.